Our Clinical Operations Associates (COAs) fill a crucial supportive role to all members of the team. COAs work to streamline the process of managing a clinical trial. A primary function of this role is to act as a central point through which virtually all clinical documentation is channeled. As documents are received, they are logged into a tracking system, scanned, and either filed in our in-house Trial Master File or forwarded to the client using a transmittal system. We have developed a proprietary process of managing regulatory documentation that provides our CRAs with a tool to ensure that site regulatory files mirror the Trial Master File, with a minimal amount of administration. This means that the site regulatory file is kept current, at a lower cost than organizations using more conventional processes.